Reviews and Protocols by CRG

Cochrane Acute Respiratory Infections Group

Full Reviews

Clinical symptoms and signs for the diagnosis of Mycoplasma pneumoniae in children and adolescents with community-acquired pneumonia
Kay Wang, Anthony Harnden, Rafael Perera, Peter Gill, Anne Thomson, David Mant

Rapid antigen detection test for group A streptococcus in children with pharyngitis.
Jérémie F Cohen, Nathalie Bertille, Robert Cohen, Martin Chalumeau

Protocols

Rapid diagnostic tests for bacterial meningitis applicable in sub-Saharan Africa
Thomas D Waite, Lilanganee Telisinghe, Maya Gobin, Olivier Ronveaux, Ana-Katya Fernandez, James M Stuart, Rob JPM Scholten

 

Cochrane Airways Group

Full reviews

Galactomannan detection for invasive aspergillosis in immunocompromized patients
Mariska M. Leeflang, Yvette J Debets-Ossenkopp, Caroline E Visser, Rob JPM Scholten, Lotty Hooft, Henk A Bijlmer, Johannes B Reitsma, Patrick MM Bossuyt, Christina M Vandenbroucke-Grauls

Protocols

Galactomannan detection in broncho-alveolar lavage fluid for invasive aspergillosis in immunocompromised patients
Koen de Heer, Marije G Gerritsen, Caroline E Visser, Mariska MG Leeflang

 

Cochrane Anaesthesia, Critical & Emergency Care Group

Full reviews

Computed tomography (CT) angiography for confirmation of the clinical diagnosis of brain death
Tim Taylor, Rob A Dineen, Dale C Gardiner, Charmaine H Buss, Allan Howatson, Nathan L Pace

Protocols

Airway physical examination tests for detection of difficult airway management in apparently normal patients
Anna Lee, Harald Herkner, Karen Hovhannisyan, Nathan Leon Pace

Peripheral venous blood gas analysis versus arterial blood gas analysis for the diagnosis of respiratory failure and metabolic disturbance in adults
Anthony L Byrne, Michael H Bennett, Nathan Leon Pace, Paul Thomas

Interleukin-6 for diagnosis of sepsis in critically ill adult patients
Daniel Molano Franco, Ingrid Arevalo-Rodriguez, Marta Roqué i Figuls, Javier Zamora

 

Cochrane Back & Neck Group

Full reviews

Physical examination for lumbar radiculopathy due to disc herniation in patients with low-back pain
Daniëlle AWM van der Windt, Emmanuel Simons, Ingrid I Riphagen, Carlo Ammendolia, Arianne P Verhagen, Mark Laslett, Walter Devillé, Rick A Deyo, Lex M Bouter, Henrica CW de Vet, Bert Aertgeerts

Red flags to screen for malignancy in patients with low-back pain
Nicholas Henschke, Christopher G. Maher, Raymond WJG Ostelo, Henrica CW de Vet, Petra Macaskill, Les Irwig

Red flags to screen for vertebral fracture in patients presenting with low-back pain
Nicholas Henschke, Christopher M Williams, Christopher G. Maher, Maurits W van Tulder, Bart W Koes, Petra Macaskill, Les Irwig

Protocols

Triage tools for detecting cervical spine injury in pediatric trauma patients
Annelie Slaar, M Matthijs Fockens, Junfeng Wang, Mario Maas, David J Wilson, J Carel Goslings, Niels WL Schep, Rick R van Rijn

 

Cochrane Bone, Joint and Muscle Trauma Group

Full Reviews

Computed tomography versus magnetic resonance imaging versus bone scintigraphy for clinically suspected scaphoid fractures in patients with negative plain radiographs
Wouter H Mallee, Junfeng Wang, Rudolf W Poolman, Peter Kloen, Mario Maas, Henrica CW de Vet, Job N Doornberg

Magnetic resonance imaging, magnetic resonance arthrography and ultrasonography for assessing rotator cuff tears in people with shoulder pain for whom surgery is being considered
Mário Lenza, Rachelle Buchbinder, Yemisi Takwoingi, Renea V Johnston, Nigel CA Hanchard, Flávio Faloppa

Physical tests for shoulder impingements and local lesions of bursa, tendon or labrum that may accompany impingement
Nigel CA Hanchard, Mário Lenza, Helen HG Handoll, Yemisi Takwoingi

Protocols

Physical tests for diagnosing anterior cruciate ligament rupture
Christian Kopkow, Toni Lange, Annika Hoyer, Jörg Lützner, Jochen Schmitt

 

Cochrane Childhood Cancer Group

Protocols

Fluorine-18-fluorodeoxyglucose (FDG) positron emission tomography (PET) computed tomography (CT) for the detection of bone, lung and lymph node metastases in rhabdomyosarcoma
Willemijn B Breunis, Lianne M Haveman, Bas Vaarwerk, Emilia C Owers, Rick R van Rijn, Henk van den Berg, Jérémie F Cohen, Leontien CM Kremer, Elvira C van Dalen, Johannes HM Merks

Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) for detecting metastases of Ewing sarcoma
Lianne M Haveman, Willemijn B Breunis, Jérémie F Cohen, Elvira C van Dalen, Emilia C Owers, Uta Dirksen, Leontien CM Kremer, Heribert Jürgens, Henk van den Berg, Johannes HM Merks

Full reviews

123I-MIBG scintigraphy and 18F-FDG-PET imaging for diagnosing neuroblastoma
Gitta Bleeker, Godelieve AM Tytgat, Judith A Adam, Huib N Caron, Leontien CM Kremer, Lotty Hooft, Elvira C van Dalen

 

Cochrane Colorectal Cancer Group

Full Reviews

Blood CEA levels for detecting recurrent colorectal cancer
Brian D Nicholson, Bethany Shinkins, Indika Pathiraja, Nia W Roberts, Tim J James, Susan Mallett, Raphael Perera, John N Primrose, David Mant

Protocols

Biomarkers for diagnosis of acute appendicitis in adults
Morwena Jane Marshall, Neil J Smart, Chris Hyde, Paul Graham Winyard, Andrew M Shaw, Ian R Daniels

Diagnostic accuracy of computed tomography for appendicitis in adults
Bo Rud, Lydur Olafsson, Thomas S Vejborg, Michael Wilhelmsen, Johannes B Reitsma, Eli D Rappeport, Peer Wille-Jørgensen

FDG PET-CT imaging for pre operative staging in patients with colorectal cancer
Fay Crawford, Heather McIntosh, Marshall Dozier, John Brush, Julie M Glanville, Malcolm G Dunlop, Andrew Renehan, David Weller, Francesca M Chappell

Guaiac-based faecal occult blood tests versus faecal immunochemical tests for colorectal cancer screening in average-risk individuals
Aafke HC van Roon, Leonie van Dam, Ann G Zauber, Marjolein van Ballegooijen, Gerard JJM Borsboom, Ewout W Steyerberg, Monique E van Leerdam, Ernst J Kuipers

Imaging modalities for the detection of posterior compartment disorders in women with obstructed defaecation syndrome
Isabelle MA van Gruting, Aleksandra Stankiewicz, Ranee Thakar, Joanna IntHout, Giulio A Santoro, Abdul H Sultan

Magnetic Resonance Imaging for Diagnosis of Acute Appendicitis
Nigel D'Souza, Anthony Thaventhiran, Richard Beable, Antony Higginson, Bo Rud

Magnetic resonance imaging (MRI) versus computed tomography (CT) for the diagnosis of lymph node metastasis in preoperative rectal cancer
Ying
Shi Sun , XiaoTing Li , Lei Tang , XiaoYan Zhang , XiaoPeng Zhang , Yong Cui , Jie Li , Jin Gu and Lin Shen

Ultrasonography for diagnosis of acute appendicitis
Jonathan RL Wild , Nicole Abdul , Judith E Ritchie , Bo Rud , Sally Freels, Richard L Nelson

 

Cochrane Common Mental Disorders Group

Protocols

Self-report screening instruments for post-traumatic stress disorder (PTSD) in survivors of traumatic experiences
Marit Sijbrandij, Johannes B Reitsma, Neil P Roberts, Iris M Engelhard, Miranda Olff, Liza P Sonneveld, Jonathan I Bisson

Cochrane Cystic Fibrosis & Genetic Disorders Group

Protocols

Biomarkers for diagnosis of Wilson's disease
Aidan Ryan, Sarah J Nolan, Paul Cook

Cochrane Dementia and Cognitive Improvement Group

Full Reviews

11C-PIB-PET for the early diagnosis of Alzheimer’s disease dementia and other dementias in people with mild cognitive impairment (MCI)
Shuo Zhang, Nadja Smailagic, Chris Hyde, Anna H Noel-Storr, Yemisi Takwoingi, Rupert McShane, Juan Feng

18F-FDG PET for the early diagnosis of Alzheimer’s disease dementia and other dementias in people with mild cognitive impairment (MCI)
Nadjia Smailagic, MarcoVacante, Chris Hyde, Steven Martin, Obioha Ukoumunne, Christos Sachpekidis

Dopamine transporter imaging for the diagnosis of dementia with Lewy bodies
Jenny McCleery, Shirlony Morgan, Kevin M Bradley, Anna H Noel-Storr, Olaf Ansorge, Chris Hyde

Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the diagnosis of dementia within a general practice (primary care) setting
Jennifer K Harrison, Patrician Fearon, Anna H Noel-Storr, Rupert McShane, David J Stott, Terry J Quinn

Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the diagnosis of dementia within a secondary care setting
Jennifer K Harrison, Patricia Fearon, Anna H Noel-Storr, Rupert McShane, David J Stott, Terry J Quinn

Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the early diagnosis of dementia across a variety of healthcare settings
Jennifer K Harrison, David J Stott, Rupert McShane, Anna H Noel-Storr, Rhiannon S Swann-Price, Terry J Quinn

IQCODE for the diagnosis of Alzheimer’s disease dementia and other dementias within a community setting
Terry J Quinn, Rupert McShane, Patricia Fearon, Camilla Young, Anna Noel-Storr, David J Stott

Mini-Cog for the diagnosis of Alzheimer's disease dementia and other dementias within a community setting
Bruce A Fage, Calvin C H Chan, Sudeep S Gill, Anna H Noel-Storr, Nathan Herrmann, Nadja Smailagic, Vasilis Nikolaou, Dallas P Seitz

Mini-Mental State Examination (MMSE) for the detection of Alzheimer's disease and other dementias in people with mild cognitive impairment (MCI)
Ingrid Arevalo-Rodriguez, Nadja Smailagic, Marta Roqué i Figuls, Augustin Ciapponi, Erick Sanchez-Perez, Antri Giannakou, Olga L Pedraza, Xavier Bonfill Cosp, Sarah Cullum

Mini-Mental State Examination (MMSE) for the detection of dementia in clinically unevaluated people aged 65 and over in community and primary care populations
Sam T Creavin, Susanna Wisniewski, Anna H Noel-Storr, Clare M Trevelyan, Thomas Hampton, Dane Rayment, Victoria M Thom, Kirsty JE Nash, Hosam Elhamoui, Rowena Milligan, Anish S Patel, Demitra V Tsivos, Tracey Wing, Emma Phillips, Sophie M Kellman, Hannah L Shackleton, Georgina F Singleton, Bethany E Neale, Martha E Watton, Sarah Cullum

Montreal Cognitive Assessment for the diagnosis of Alzheimer’s disease and other dementias
Daniel HJ Davis, Sam T Creavin, Jennifer LY Yip, Anna H Noel-Storr, Carol Brayne, Sarah Cullum

Plasma and cerebrospinal fluid amyloid beta for the diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI)
Craig Ritchie, Nadja Smailagic, Anna H Noel-Storr, Yemisi Takwoingi, Leon Flicker, Sam Mason, Rupert McShane

Regional Cerebral Blood Flow Single Photon Emission Computed Tomography for detection of Frontotemporal dementia in people with suspected dementia
Hilary A Archer, Nadja Smailagic, Christeena John, Robin B Holmes, Yemisi Takwoingi, Elizabeth J Coulthard, Sarah Cullum

Protocols

18F PET ligands for the early diagnosis of Alzheimer’s disease dementia and other dementias in people with mild cognitive impairment (MCI)
Gabriel Martínez, Leon Flicker, Robin WM Vernooij, Paulina Fuentes Padilla, Javier Zamora, Marta Roqué i Figuls, Gerard Urrútia, Xavier Bonfill Cosp

AD-8 for diagnosis of dementia across a variety of healthcare settings
Kirsty Hendry, Rosalind Lees, Rupert McShane, Anna H Noel-Storr, David J Stott, Terry J Quinn

APOE-ε4 allele for the diagnosis of Alzheimer's and other dementia disorders in people with mild cognitive impairment in a community setting
Lyzel S Elias-Sonnenschein, Wolfgang Viechtbauer, Inez Ramakers, Obioha Ukoumunne, Franz RJ Verhey, Pieter J Visser

APOE-ε4 allele for the diagnosis of Alzheimer's and other dementia disorders in people with mild cognitive impairment in a primary care setting
Lyzel S Elias-Sonnenschein, Wolfgang Viechtbauer, Inez Ramakers, Obioha Ukoumunne, Franz RJ Verhey, Pieter J Visser

APOE-ε4 allele for the diagnosis of Alzheimer's and other dementia disorders in people with mild cognitive impairment in a secondary care setting
Lyzel S Elias-Sonnenschein, Wolfgang Viechtbauer, Inez Ramakers, Obioha Ukoumunne, Franz RJ Verhey, Pieter J Visser

CSF tau and the CSF tau/ABeta ratio for the diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI)
Craig Ritchie, Nadja Smailagic, Emma C Ladds, Anna H Noel-Storr, Obioha Ukoumunne, Steven Martin.

Depression rating scales for detection of major depression in people with dementia
Julia G Kirkham, Yemisi Takwoingi, Terry J Quinn, Mark Rapoport, Krista L Lanctôt, Colleen J Maxwell, Nathan Herrmann, Sudeep S Gill, Paula A Rochon, Dallas P Seitz

Mini-Cog for the diagnosis of Alzheimer’s disease dementia and other dementias within a primary care setting
Dallas P Seitz, Bruce A Fage, Calvin CH Chan, Sudeep S Gill, Nathan Herrmann, Nadja Smailagic, Vasilis Nikolaou

Mini-Cog for the diagnosis of Alzheimer’s disease dementia and other dementias within a secondary care setting
Calvin CH Chan, Bruce A Fage, Nadja Smailagic, Sudeep S Gill, Nathan Herrmann, Vasilis Nikolaou, Dallas P Seitz

Neuropsychological tests for the diagnosis of Alzheimer’s disease dementia and other dementias: a generic protocol for crosssectional and delayedverification studies
Daniel HJ Davis , Sam T Creavin , Anna Noel
Storr , Terry J Quinn , Nadja Smailagic , Chris Hyde , Carol Brayne , Rupert McShane, Sarah Cullum

Plasma and Cerebrospinal fluid (CSF) Abeta42 for the differential diagnosis of Alzheimer's disease dementia in participants diagnosed with any dementia subtype in a specialist care setting
Michelle Kokkinou, Nadja Smailagic, Anna H Noel-Storr, Chris Hyde, Obioha Ukoumunne, Rosie E Worrall, Anja Hayen, Meera Desai, Craig Ritchie

The role of MRI in the early diagnosis of Alzheimer’s disease or other dementias in persons with mild cognitive impairment (MCI)
Graziella Filippini, Giovanni Casazza, Alessandro-Giacco Bellatorre, Chiara Lista, Piergiorgio Duca, Deirdre Beecher, Giorgio Costantino, Chiara Falcone, Giovanna Zamboni, Enrica Cavedo, Giovanni Frisoni

 

Cochrane Developmental, Psychosocial and Learning Problems Group

Protocols

Diagnostic instruments for autism spectrum disorder (ASD)
Leonora Vllasaliu, Katrin Jensen, Stephanie Hoss, Marie Landenberger, Marianne Menze, Magdalena Schütz, Krystyna Ufniarz, Meinhard Kieser, Christine M Freitag

Diagnostic tests for Autism Spectrum Disorders (ASD) in preschool children
Aarti Samtani, Katy Sterling-Levis, Rob JPM Scholten, Susan Woolfenden, Lotty Hooft, Katrina Williams

 

Cochrane Drugs and Alcohol Group

Protocols

Brief alcohol questionnaires for identifying hazardous, harmful and dependent alcohol use in primary care
Lesley A Smith, David Foxcroft, Aisha Holloway, Silvia Minozzi, Giovanni Casazza

 

Cochrane ENT Group

Protocols

MRI versus CT for detecting cartilage invasion in patients with laryngeal and hypopharyngeal squamous cell carcinoma
Inge Wegner, Lotty Hooft, Johannes B Reitsma, Frank A Pameijer, Remco de Bree, Inge Stegeman

MRI versus CT versus 18F-FDG PET-CT for detecting lymph node metastases in patients with head and neck squamous cell carcinoma
Inge Wegner, Lotty Hooft, Johannes B Reitsma, Frank A Pameijer, Otto Hoekstra, Remco de Bree, Inge Stegeman

Tests for screening for hearing loss in children about to start school
Zhivko Zhelev, Chris Hyde, John E Fitzgerald, Obioha Ukoumunne, Simon Briscoe, Julia Chisnell, Bogdan Grigore

Cochrane Eyes and Vision Group

Full Reviews

Optical coherence tomography (OCT) for detection of macular oedema in patients with diabetic retinopathy
Gianni Virgili, Francesca Menchini, Giovanni Casazza, Ruth Hogg, Radha Das, Xue Wang, Manuele Michelessi

Optic nerve head and fibre layer imaging for diagnosing glaucoma
Manuele Michelessi, Ersilia Lucenteforte, Francesco Oddone, Miriam Brazzelli, Mariacristina Parravano, Sara Franchi, Sueko M Ng, Gianni Virgili

Protocols

Tests for detecting strabismus in children age 1 to 6 years in the community
Vijay Tailor, Sara Balduzzi, Sarah Hull, Jugnoo Rahi, Christine Schmucker, Gianni Virgili, Annegret Dahlmann-Noor

 

Cochrane Gynaecological, Neuro-oncology & Orphan Cancers Group

Full Reviews

Intraoperative frozen section analysis for the diagnosis of early stage ovarian cancer in suspicious pelvic masses
Nithya DG Ratnavelu, Andrew P Brown, Susan Mallett, Rob JPM Scholten, Amit Patel, Christina Founta, Khadra Galaal, Paul Cross, Raj Naik

Laparoscopy for diagnosing resectability of disease in patients with advanced ovarian cancer
Marianne J Rutten, Mariska MG Leeflang, Gemma G Kenter, Ben Willem J Mol, Marrije Buist

Polymerase chain reaction blood tests for the diagnosis of invasive aspergillosis in immunocompromised people
Mario Cruciani, Carlo Mengoli, Juergen Loeffler, Peter Donnelly, Rosemary Barnes, Brian L Jones, Lena Klingspor, Oliver Morton, Johan Maertens

Sentinel node assessment for diagnosis of groin lymph node involvement in vulval cancer
Theresa A Lawrie, Amit Patel , Pierre PL Martin-Hirsch, Andrew Bryant, Nithya DG Ratnavelu, Raj Naik, Angela Ralte

Triage with human papillomavirus (HPV) testing versus repeat cytology for underlying high-grade cervical intra-epithelial neoplasia in women with minor cytological lesions
Marc Arbyn, Cindy Simoens, Frank Buntinx, Pierre PL Martin-Hirsch, Evangelos Paraskevaidis, Walter JP Prendiville

Protocols

(1→3)β-D-glucan testing for the detection of invasive fungal infections in immunocompromised patients
Robert L Schmidt, Robert Schlaberg, Kimberly Hanson

Cytology versus HPV testing for cervical cancer screening in the general population
George Koliopoulos, Marc Arbyn, Pierre PL Martin-Hirsch, Maria Kyrgiou, Walter JP Prendiville, Evangelos Paraskevaidis

Low cost versus other screening tests to detect cervical cancer or precancer in developing countries
Marc Arbyn , Amy Fisher , Pierre PL Martin
Hirsch , FangHui Zhao, Youlin Qiao

Magnetic resonance perfusion for differentiating low grade from high grade gliomas at first presentation
Jill M Abrigo, Wilson Wai San Tam, Michael G Hart, Eric Ka Chai Law, Joey SW Kwong J, James M Provenzale

Sentinel node biopsy for diagnosis of pelvic lymph node involvement in early stage cervical cancer
Karen K L Chan, Christine Ang, Andrew Bryant, Javier Zamora, Raj Naik

Symptoms, ultrasound imaging and biochemical markers alone or in combination for the diagnosis of ovarian cancer in women with symptoms suspicious of ovarian cancer
Nirmala Rai, Rita Champaneria, Kim Snell, Susan Mallett, Susan E Bayliss, Richard D Neal, Moji Balogun, Sean Kehoe, Jonathan J Deeks, Sudha Sundar, Clare Davenport

 

Cochrane Gynaecology & Fertility Group

Full reviews

Blood biomarkers for the non-invasive diagnosis of endometriosis
Vicki Nisenblat, Patrick MM Bossuyt, Rabia Shaikh, Cindy Farquhar, Vanessa Jordan, Carola Scheffers, Ben Willem J Mol, Neil Johnson, M Louis

Combination of the non-invasive tests for the diagnosis of endometriosis
Vicki Nisenblat, Lucy Prentice, Patrick MM Bossuyt, Cindy Farquhar, Louise M Hull, Neil Johnson

Endometrial biomarkers for the non-invasive diagnosis of endometriosis
Devashana Gupta, M Louise Hull, Ian Fraser, Laura Miller, Patrick MM Bossuyt, Neil Johnson, Vicki Nisenblat

Urinary biomarkers for the non-invasive diagnosis of endometriosis
Emily Liu, Vicki Nisenblat, Cindy Farquhar, Ian Fraser, Patrick MM Bossuyt, Neil Johnson, M Louise Hull

Imaging modalities for the non-invasive diagnosis of endometriosis
Vicki Nisenblat, Patrick MM Bossuyt, Cindy Farquhar, Neil Johnson, M Louise Hull

Protocols

Chlamydia antibody titer testing versus hysterosalpingography for detection of tubal pathology in subfertile women
Sjors F Coppus, M Chandra , A Coomarasamy, Neil Johnson, Fulco Van der Veen, Patrick MM Bossuyt, Ben Willem J Mol

Three-dimensional saline infusion sonohysterography for the diagnosis of focal intracavitary lesions
Lotte L Nieuwenhuis, Frederik JR Hermans, AJ Marjolein Bij de Vaate, Mariska MG Leeflang, Hans AM Brölmann, Ben Willem J Mol, T Justin Clark, Judith AF Huirne

 

Cochrane Hepato-Biliary Group

Full Reviews

Capsule endoscopy for the diagnosis of oesophageal varices in people with chronic liver disease or portal vein thrombosis
Agostino Colli, Juan C Gana, Dan Turner, Jason Yap, Thomasin Adams-Webber, Simon C Ling, Giovanni Casazza

Endoscopic retrograde cholangiopancreatography versus intraoperative cholangiography for diagnosis of common bile duct stones
Kurinchi Selvan Gurusamy, Vanja Giljaca, Yemisi Takwoingi, David Higgie, Goran Poropat, Davor Štimac, Brian R Davidson

Endoscopic ultrasound versus magnetic resonance cholangiopancreatography for common bile duct stones
Vanja Giljac, Kurinchi Selvan Gurusamy, YemisiTakwoingi, David Higgie, Goran Poropat, Davor Štimac, Brian R Davidson

Transient elastography for diagnosis of stages of hepatic fibrosis and cirrhosis in people with alcoholic liver disease
Chavdar S Pavlov, Giovanni Casazza, Dimitrinka Nikolova, Emmanuel Tsochatzis, Andrew K Burroughs, Vladimir T Ivashkin, Christian Gluud

Ultrasonography for diagnosis of alcoholic cirrhosis in people with alcoholic liver disease
Chavdar S Pavlov, Giovanni Casazza, Marianna Semenistaia, Dimitrinka Nikolova, Emmanuel Tsochatzis, Ekaterina Liusina, Vladimir T Ivashkin, Christian Gluud

Ultrasound versus liver function tests for diagnosis of common bile duct stones
Kurinchi Selvan Gurusamy, Vanja Giljaca, Yemisi Takwoingi, David Higgie, Goran Poropat, Davor Štimac, Brian R Davidson

Protocols

Combination of magnetic resonance cholangiopancreatography and conventional magnetic resonance imaging for the diagnosis of bile duct stenosis
Augusto José Cavalcanti Neto, Suzana AS Lustosa, Giovanni Casazza, Carolina Reis, Marcelle Procopio Gomes, Andreia Cristina Feitosa Do Carmo, Giuseppe D'Ippolito, Delcio Matos

Contrast-enhanced ultrasound compared with computed tomography, magnetic resonance imaging, and positron emission tomography for diagnosing liver metastases in people with newly diagnosed colorectal cancer
Martin Lund, Thomas A Bjerre, Henning Grønbæk, Frank Mortensen, Per Kragh Andersen

FibroTest, transient elastography method, and combined FibroTest and transient elastography method for diagnosis of severe hepatic fibrosis and cirrhosis in adults with chronic hepatitis C
Chavdar S Pavlov, Giovanni Casazza, Dimitrinka Nikolova, Emmanuel Tsochatzis, Vladimir T Ivashkin, Christian Gluud

Forns index and 'FIB4' for staging of fibrosis in adults with chronic hepatitis C
Maria Kalafateli, Kurinchi Selvan Gurusamy, Anna H Noel-Storr, Andrew K Burroughs, Emmanuel Tsochatzis

Magnetic resonance imaging, computer tomography scan, and oesophagography for the diagnosis of oesophageal varices in patients with chronic liver disease or portal vein thrombosis
Juan Cristobal Gana, Dan Turner, Jason Yap, Thomasin Adams-Webber, Natalie Rashkovan, Simon C Ling

Molecular and antigen detection tests for leptospirosis
Bada Yang, Sophia G de Vries, Benjamin J Visser, Ingeborg M Nagel, Marga GA Goris, Mariska MG Leeflang, Martin P Grobusch, Rudy A Hartskeerl

Non-invasive test of liver fibrosis for the diagnosis of oesophageal varices in patients with chronic liver disease or portal vein thrombosis
Juan Cristobal Gana, Dan Turner, Jason Yap, Thomasin Adams-Webber, Natalie Rashkovan, Simon C Ling

Platelet count, spleen length, and platelet count/spleen length ratio for the diagnosis of oesophageal varices in patients with chronic liver disease or portal vein thrombosis
Juan Cristobal Gana, Dan Turner, Jason Yap, Thomasin Adams-Webber, Natalie Rashkovan, Simon C Ling

Serological laboratory tests for diagnosis of human leptospirosis in patients presenting with clinical symptoms
Marga Goris, Kimberly Rachel Boer, Meerjam Bouman-Strijker, Rudy Hartskeerl, Cees Lucas, Mariska Leeflang

Transabdominal ultrasound or endoscopic ultrasound for diagnosis of gallbladder polyps
Sarah Z Wennmacker, Mark P Lamberts, Joost PH Drenth, Kurinchi Selvan Gurusamy, Cornelis JHM van Laarhoven

Transient ultrasound elastography and magnetic resonance elastography for the diagnosis of oesophageal varices in patients with chronic liver disease or portal vein thrombosis
Juan Cristobal Gana, Dan Turner, Jason Yap, Thomasin Adams-Webber, Natalie Rashkovan, Simon C Ling

 

Cochrane IBD Group

Protocols

Biomarkers for assessing disease activity in inflammatory bowel disease
Mahmoud Mosli, Marianne Fahmy, Sushil Garg, Sean G Feagan, Kenneth A Baker, GY Zou, John K MacDonald, William J Sandborn, Nilesh Chande

 

Cochrane Incontinence Group

Protocols

Accuracy of MRI, ultrasound and vaginal assessment for the diagnosis of levator ani muscle avulsion in women
Isabelle MA van Gruting, Kim WM Van Delft, Ranee Thakar, Joanne IntHout, Abdul H Sultan

 

Cochrane Infectious Diseases Group

Full Reviews

Circulating antigen tests and urine reagent strips for diagnosis of active schistosomiasis in endemic areas
Ochodo EA, Gopalakrishna G, Spek B, Reitsma JB, van Lieshout L, Polman K, Lamberton P, Patrick MM Bossuyt, Mariska MG Leeflang

GenoType® MTBDRsl assay for resistance to second-line anti-tuberculosis drugs
Grant Theron, Jonny Peter, Marty Richardson, Rob Warren, Keertan Dheda, Karen R Steingart

Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in HIV-positive adults
Maunank Shah, Colleen Hanrahan, Zhuo Yu Wang, Nandini Dendukuri, Stephen D Lawn, Claudia M Denkinger, Karen R Steingart

Rapid diagnostic tests for diagnosing uncomplicated non-falciparum or Plasmodium vivax malaria in endemic countries
Katharine Abba, Amanda J Kirkham, Piero L Olliaro, Jonathan J Deeks, Sarah Donegan, Paul Garner, Yemisi Takwoingi

Rapid diagnostic tests for diagnosing uncomplicated P. falciparum malaria in endemic countries
Katharine Abba, Jonathan J Deeks, Piero Olliaro, Cho-Min Naing, Sally M Jackson, Yemisi Takwoingi, Sarah Donegan, Paul Garner

Rapid tests for the diagnosis of visceral leishmaniasis in patients with suspected disease
Marleen Boelaert, Kristien Verdonck, Joris Menten, Temmy Sunyoto, Johan van Griensven, Francois Chappuis, Suman Rijal

Xpert® MTB/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults.
Karen R Steingart, Ian Schiller, David J Horne, Madhukar Pai, Catharina C Boehme, Nandini Dendukuri

Protocols

NS1 antigen detecting assays for diagnosing acute dengue infection in people living in or returning from endemic countries
Martina Casenghi, Cara Kosack, Roland Li, Matthieu Bastard, Nathan Ford

Rapid Diagnostic Tests for Typhoid and Paratyphoid (Enteric) Fever
Lalith Wijedoru, Sarah Donegan, Christopher Parry

Symptom- and chest-radiography screening for active pulmonary tuberculosis in HIV-negative adults and adults with unknown HIV status
Anna H van't Hoog, Miranda Langendam, Ellen Mitchell, Frank Cobelens, David Sinclair, Mariska M Leeflang, Knut Lönnroth

 

Cochrane Injuries Group

Full Reviews

Thromboelastography (TEG) and rotational thromboelastometry (ROTEM) for trauma-induced coagulopathy in adult trauma patients with bleeding
Harriet Hunt, Simon Stanworth, Nicola Curry, Tom Woolley, Chris Cooper, Obioha Ukoumunne, Zhivko Zhelev, Chris Hyde

 

Cochrane Kidney & Transplant Group

Full reviews

Cardiac testing for coronary artery disease in potential kidney transplant recipients
Louis W Wang, Magid A Fahim, Andrew Hayen, Ruth L Mitchell, Laura Baines, Stephen Lord, Jonathan C Craig, Angela C Webster

Clinical symptoms, signs and tests for identification of impending and current water-loss dehydration in older people
Lee Hooper, Asmaa Abdelhamid, Natalie J Attreed, Wayne W Campbell, Adam M Channell, Philippe Chassagne, Kennith R Culp, Stephen J Fletcher, Matthew B Fortes, Nigel Fuller, Phyllis M Gaspar, Daniel J Gilbert, Adam C Heathcote, Mohannad W Kafri, Fumiko Kajii, Gregor Lindner, Gary W Mack, Janet C Mentes, Paolo Merlani, Rowan A Needham, Marcel GM Olde Rikkert, Andreas Perren, James Powers, Sheila C Ranson, Patrick Ritz, Anne M Rowat, Fredrik Sjöstrand, Alexandra C Smith, Jodi JD Stookey, Nancy A Stotts, David R Thomas, Angela Vivanti, Bonnie J Wakefield, Nana Waldréus, Neil P Walsh, Sean Ward, John F Potter, Paul Hunter

Dimercaptosuccinic acid scan or ultrasound in screening for vesicoureteral reflux among children with urinary tract infections
Nader Shaikh, Russell B Spingarn, Stephanie W Hum

Procalcitonin, C-reactive protein, and erythrocyte sedimentation rate for the diagnosis of acute pyelonephritis in children
Nader Shaikh, Jessica L Borrell, Josh Evron, Mariska MG Leeflang

Protocols

 

Cochrane Lung Cancer Group

Full reviews

PET-CT for assessing mediastinal lymph node involvement in patients with suspected resectable non-small cell lung cancer
Mia Schmidt-Hansen, David R Baldwin, Elise Hasler, Javier Zamora, Victor Abraira, Marta Roqué i Figuls

 

Cochrane Metabolic and Endocrine Disorders Group

Protocols

Calcitonin testing for detection of medullary thyroid cancer in patients with thyroid nodules
Hans HG Verbeek , Jan Willem B de Groot , Wim J Sluiter , Anneke C Muller Kobold , John TM Plukker, Thera P Links

Scoring systems to screen for diabetic peripheral neuropathy
Zhirong Yang, Ru Chen, Yuan Zhang, Yuansheng Huang, Tianpei Hong, Feng Sun, Linong Ji, Siyan Zhan

Simple tests to screen for diabetic peripheral neuropathy
Zhirong Yang, Yuan Zhang, Ru Chen, Yuansheng Huang, Linong Ji, Feng Sun, Tianpei Hong, Siyan Zhan

 

Cochrane Neonatal Group

Protocols

Clinical assessment for diagnosing congenital heart disease in newborn infants with Down syndrome
William McGuire, Peter W Fowlie, Johannes B Reitsma

C-reactive protein for diagnosing late-onset infection in newborn infants
Jennifer VE Brown, Nicholas Meader, Jemma Cleminson, William McGuire

Diagnostic accuracy of pulse oximetry screening for critical congenital heart defects
Maria N Plana, Javier Zamora, Gautham Suresh, Luis Fernandez-Pineda, Shakila Thangaratinam, Andrew K Ewer

Molecular assays for the diagnosis of sepsis in neonates
Mohan Pammi, Angela Flores, James Versalovic, Mariska MG Leeflang

 

Cochrane Neuromuscular Group

Protocols

Anti-GM1 antibody testing for multifocal motor neuropathy
Filip Eftimov, Michael PT Lunn, Mariska M.G. Leeflang, Ivo N van Schaik

 

Cochrane Oral Health Group

Full Reviews

Clinical assessment to screen for the detection of oral cavity cancer and potentially malignant disorders in apparently healthy adults
Tanya Walsh, Joseph LY Liu, Paul Brocklehurst, Anne-Marie Glenny, Mark Lingen, Alexander R Kerr, Graham Ogden, Saman Warnakulasuriya, Crispian Scully

Diagnostic tests for oral cancer and potentially malignant disorders in patients presenting with clinically evident lesions
Richard Macey, Tanya Walsh, Paul Brocklehurst, Alexander R Kerr, Joseph LY Liu, Mark W Lingen, Graham R Ogden, Saman Warnakulasuriya, Crispian Scully

 

Cochrane Pregnancy and Childbirth Group

Full reviews

First trimester serum tests for Down's syndrome screening
Sarah K Alldred, Yemisi Takwoingi, Boliang Guo, Mary Pennant, Jonathan J Deeks, James P Neilson, Zarko Alfirevic

Second trimester serum tests for Down's Syndrome screening
S Kate Alldred, Jonathan J Deeks, Boliang Guo, James P Neilson, Zarko Alfirevic

Urine tests for Down's syndrome screening
S Kate Alldred, Boliang Guo, Yemisi Takwoingi,  Mary Pennant, Susanna Wisniewski, Jonathan J Deeks, James P Neilson, Zarko Alfirevic

Protocols

Antenatal screening for Down's syndrome: generic protocol
S Kate Alldred, Jonathan J Deeks, James P Neilson, Zarko Alfirevic

Diagnostic accuracy of biochemical tests of placental function versus ultrasound assessment of fetal size for stillbirth and small-for-gestational-age infants
Alexander EP Heazell, Dexter JL Hayes, Melissa Whitworth, Yemisi Takwoingi, Susan E Bayliss, Clare Davenport

Genomics-based non-invasive prenatal testing for detection of fetal chromosomal aneuploidy in pregnant women
Mylène Badeau, Carmen Lindsay, Jonatan Blais, Yemisis Takwoingi, Sylvie Langlois, France Légaré, Yves Giguère, Alexis F Turgeon, William Witteman, François Rousseau

 

Cochrane Schizophrenia Group

Full reviews

First rank symptoms for schizophrenia
Karla Soares-Weiser, Nicola Maayan, Hanna Bergman, Clare Davenport, Amanda J Kirkham, Sarah Grabowski, Clive E Adams

Voxel-based morphometry for separation of schizophrenia from other types of psychosis in first-episode psychosis
Lena Palaniyappan, Nicola Maayan, Hanna Bergman, Clare Davenport, Clive E Adams, Karla Soares-Weiser

Protocols

Operational Criteria Checklist for Psychotic Illness and Affective Illness (OPCRIT+) for diagnosing schizophrenia in people with psychotic symptoms
Hannah Bergman, Atoosa Khodabakhsh, Nicola Maayan, Amanda J Kirkham, Clive E Adams, Karla Soares-Weiser

Schedule for Affective Disorders and Schizophrenia for School-Age Children (K-SADS) for diagnosing schizophrenia in children and adolescents with psychotic symptoms
Hanna Bergman, Nicola Maayan, Amanda J Kirkham, Clive E Adams, Karla Soares-Weiser

 

Cochrane Skin Group

Protocols

Tests to assist in the diagnosis of cutaneous melanoma in adults: a generic protocol
Jac Dinnes, Rubeta N Matin, Jacqueline F Moreau, Lopa Patel, Sue A Chan, Naomi Chuchu, Susan E Bayliss, Matthew Grainge, Yemisi Takwoingi, Clare Davenport, Fiona M Walter, Colin Fleming, Julia Schofield, Neil Shroff, Kathie Godfrey, Colette O'Sullivan, Jonathan J Deeks, Hywel C Williams

Tests to assist in the diagnosis of keratinocyte skin cancers in adults: a generic protocol
Jac Dinnes, Kai Yuen Wong, Abha Gulati, Naomi Chuchu, Jo Leonardi-Bee, Susan E Bayliss, Yemisi Takwoingi, Clare Davenport, Rubeta N Matin, Fiona J Bath-Hextall, Abhilash A Jain, John T Lear, Richard Motley, Jonathan J Deeks, Hywel C Williams, Kathie Godfrey, Colette O'Sullivan

 

Cochrane STI Group

Protocols

Rapid point of care test for detecting urogenital Chlamydia trachomatis infection in nonpregnant women and men at reproductive age
Carlos F Grillo-Ardila, Marcela Torres, Hernando G Gaitán, Javier Zamora

 

Cochrane Stroke Group

Full reviews

Computed tomography angiography or magnetic resonance angiography for detection of intracranial vascular malformations in patients with intracerebral haemorrhage
Colin B Josephson, Philip M White, Ashma Krishan, Rustam Al-Shahi Salman

Magnetic resonance imaging versus computed tomography for detection of acute vascular lesions in patients presenting with stroke symptoms
Miriam Brazzelli, Peter AG Sandercock, Francesca M Chappell, Maria Grazia Celani, Enrico Righetti, Nicholas Arestis, Joanna M Wardlaw, Jonathan J Deeks

Protocols

Doppler ultrasound, CT angiography, MR angiography, and contrast-enhanced MR angiography versus intra-arterial angiography for moderate and severe carotid stenosis in symptomatic patients
Francesca M Chappell, Joanna M Wardlaw, Miriam Brazzelli, Jonathan JK Best

Non-invasive imaging to detect vertebral artery stenosis
Arthur G Kurvers, Annette Compter, Joanna M Wardlaw, Yolanda van der Graaf, Paul J Nederkoor

Prehospital stroke scales as screening tools for early identification of stroke and transient ischemic attack
Greg Walker, Samuel Yip, Zhivko Zhelev, Nicholas Henschke

Transcranial Doppler sonography for detecting stenosis or occlusion of intracranial arteries in people with acute ischaemic stroke
Alessia Mattioni, Miriam Brazzelli, Silvia Cenciarelli, Tatiana Mazzoli, Massimo Del Sette, Carlo Gandolfo, Marinella Marinoni, Cinzia Finocchi, Valentina Saia, Paolo Eusebi, Peter AG Sandercock, Stefano Ricci.

 

Cochrane Tobacco Addiction Group

Protocols

Serum or plasma ferritin concentration as an index of iron deficiency and overload
Maria N Garcia-Casal, Sant-Rayn Pasricha, Ricardo X Martinez, Lucero Lopez-Perez, Juan P Peña-Rosas

 

Cochrane UGI & Pancreatic Diseases Group

Full Reviews

Diagnostic accuracy of endoscopic ultrasonography (EUS) for the preoperative locoregional staging of primary gastric cancer
Simone Mocellin, Sandro Pasquali

Diagnostic accuracy of different imaging modalities following computed tomography (CT) scanning for assessing the resectability with curative intent in pancreatic and periampullary cancer
DomenicoTamburrino, Deniece Riviere, Mohammad Yaghoobi, Brian R Davidson, Kurinchi Selvan Gurusamy

Diagnostic accuracy of laparoscopy following computed tomography (CT) scanning for assessing the resectability with curative intent in pancreatic and periampullary cancer
Victoria B Allen, Kurinchi Selvan Gurusamy, Yemisi Takwoingi, Amun Kalia, Brian R Davidson

Protocols

Carbon dioxide detection for diagnosis of inadvertent respiratory tract placement of enterogastric tubes in children
Fiona Smith, Agi Holland, Kay Penny, Marie Elen, Deborah McGirr

Carbon dioxide detection for testing nasogastric tube placement in adults
Agi Holland, Fiona Smith, Kay Penny

Imaging modalities for characterising focal pancreatic lesions
Kurinchi Selvan Gurusamy, Brian R Davidson

Non-invasive diagnostic tests for Helicobacter pylori infection
Kurinchi Selvan Gurusamy, Mohammad Yaghoobi, Brian R Davidson

Pancreatic amylase in drain fluid for the diagnosis of pancreatic leak in post pancreatic resection
Kurinchi S Gurusamy, Yaghoobi M, Brian R Davidson

Serum amylase and lipase and urinary trypsinogen and amylase for diagnosis of acute pancreatitis and serum C-reactive protein, procalcitonin and lactate dehydrogenase for the diagnosis of pancreatic necrosis
Kurinchi S Gurusamy, Brian R Davidson

Ultrasonography for confirmation of gastric tube placement
Hiraku Tsujimoto, Yasushi Tsujimoto, Yukihiko Nakata, Mai Akazawa, Yuki Kataoka

 

Cochrane Vascular Group

Full Reviews

Ankle brachial index for the diagnosis of lower limb peripheral arterial disease
Fay Crawford, Karen Welch, Alina Andras, Francesca M Chappell

D-dimer test for excluding the diagnosis of pulmonary embolism
Fay Crawford, Alina Andras, Karen Welch, Karen Sheares, David Keeling, Francesca M Chappell

Protocols

D-dimer test for excluding the diagnosis of pulmonary embolism
Francesca M Chappell, Alina Andras, Karen Welch, Marcello Di Nisio, Lindsay Robertson, Marlene Stewart, Fay Crawford

Duplex ultrasound for the detection of stenosis after peripheral arterial bypass grafting using autologous vein
Francesca M Chappell, Alina Andras, Karen Welch, Crispian Oates

Duplex ultrasound for the diagnosis of symptomatic deep vein thrombosis in the lower limb
Francesca M Chappell, Fay Crawford, Alina Andras, Steve Goodacre, James E McCaslin, Karen Welch, Crispian Oates

Imaging for the exclusion of pulmonary embolism in pregnancy
Paulien G de Jong, Thijs E van Mens, Mariska MG Leeflang, Saskia Middeldorp, Mathilde Nijkeuter

Positron emission tomography (PET) for the detection of vascular graft infections
Viviana Brito, Cecilia Loudet, Augustin Ciapponi, Joey SW Kwong, Laura Capoccia

Ultrasonography for clinically suspected upper extremity deep vein thrombosis
Marcello Di Nisio, Patrick MM Bossuyt, Ettore Porreca, Geerte van Sluis, Harry R Büller, Franco Cuccurullo, Anne WS Rutjes

Ultrasonography for endoleak detection after endoluminal abdominal aortic aneurysm repair
Iosief Abraha , Rita De Florio , Giovanni Casazza , Piergiorgio Duca , Basso Parente , Francesco Cozzolino , Paolo Eusebi , Rosalba E Rocchi, Alessandro Montedori